H.J.P Fokkenrood

Innovative strategies for
intermittent claudication

towards a stepped care approach and new outcome measures



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  2.  Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL, et al. ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease. Circulation. 2006 Mar 21;113(11):e463-654. PubMed PMID: 16549646. Epub 2006/03/22. eng.
  3.  Layden J, Michaels J, Bermingham S, Higgins B, Guideline Development G. Diagnosis and management of lower limb peripheral arterial disease: summary of NICE guidance. Bmj. 2012;345:e4947. PubMed PMID: 22875949.
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  5.  Fokkenrood HJ, Lauret GJ, Scheltinga MR, Spreeuwenberg C, de Bie RA, Teijink JA. Multidisciplinary treatment for peripheral arterial occlusive disease and the role of eHealth and mHealth. Journal of multidisciplinary healthcare. 2012;5:257-63. PubMed PMID: 23093906. Pubmed Central PMCID: 3476374. Epub 2012/10/25. eng.
  6.  Mays RJ, Regensteiner JG. Exercise therapy for claudication: latest advances. Current treatment options in cardiovascular medicine. 2013 Apr;15(2):188-99. PubMed PMID: 23436041. Pubmed Central PMCID: 3627476. Epub 2013/02/26. eng.
  7.  Gardner AW, Parker DE, Montgomery PS, Scott KJ, Blevins SM. Efficacy of quantified home-based exercise and supervised exercise in patients with intermittent claudication: a randomized controlled trial. Circulation. 2011 Feb 8;123(5):491-8. PubMed PMID: 21262997. Pubmed Central PMCID: 3154843. Epub 2011/01/26. eng.
  8.  Saxton JM, Zwierska I, Blagojevic M, Choksy SA, Nawaz S, Pockley AG. Upper- versus lower-limb aerobic exercise training on health-related quality of life in patients with symptomatic peripheral arterial disease. J Vasc Surg. 2011 May;53(5):1265-73. PubMed PMID: 21215558.
  9.  Lauret GJ, van Dalen HC, Hendriks HJ, van Sterkenburg SM, Koelemay MJ, Zeebregts CJ, et al. When is supervised exercise therapy considered useful in peripheral arterial occlusive disease? A nationwide survey among vascular surgeons. Eur J Vasc Endovasc Surg. 2012 Mar;43(3):308-12. PubMed PMID: 22240337. Epub 2012/01/14. eng.
  10.  Makris GC, Lattimer CR, Lavida A, Geroulakos G. Availability of supervised exercise programs and the role of structured home-based exercise in peripheral arterial disease. Eur J Vasc Endovasc Surg. 2012 Dec;44(6):569-75; discussion 76. PubMed PMID: 23034408. Epub 2012/10/05. eng.
  11.  Fokkenrood HJ, Bendermacher BL, Lauret GJ, Willigendael EM, Prins MH, Teijink JA. Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication. Cochrane Database Syst Rev. 2013 Aug 23;8:CD005263. PubMed PMID: 23970372.
  12.  Nicolai  SP, Teijink JA, Prins MH. Multicenter randomized clinical trial of supervised exercise therapy with or without feedback versus walking advice for intermittent claudication. J Vasc Surg. 2010 Aug;52(2):348-55. PubMed PMID: 20478681. Epub 2010/05/19. eng.
  13.  Bermingham SL, Sparrow K, Mullis R, Fox M, Shearman C, Bradbury A, et al. The Cost-effectiveness of Supervised Exercise for the Treatment of Intermittent Claudication. Eur J Vasc Endovasc Surg. 2013 Dec;46(6):707-14. PubMed PMID: 24103792.
  14.  Spronk S, Bosch JL, den Hoed PT, Veen HF, Pattynama PM, Hunink MG. Intermittent claudication: clinical effectiveness of endovascular revascularization versus supervised hospital-based exercise training--randomized controlled trial. Radiology. 2009 Feb;250(2):586-95. PubMed PMID: 19188327.
  15.  Lauret GJ, Gijsbers HJ, Hendriks EJ, Bartelink ML, de Bie RA, Teijink JA. The ClaudicatioNet concept: design of a national integrated care network providing active and healthy aging for patients with intermittent claudication. Vasc Health Risk Manag. 2012;8:495-503. PubMed PMID: 22942648. Pubmed Central PMCID: 3428244. Epub 2012/09/04. eng.
  16.  O'Brien-Irr MS, Harris LM, Dosluoglu HH, Dryjski ML. Endovascular intervention for treatment of claudication: is it cost-effective? Annals of vascular surgery. 2010 Aug;24(6):833-40. PubMed PMID: 20638623. Epub 2010/07/20. eng.
  17.  Mazari FA, Khan JA, Carradice D, Samuel N, Gohil R, McCollum PT, et al. Economic analysis of a randomized trial of percutaneous angioplasty, supervised exercise or combined treatment for intermittent claudication due to femoropopliteal arterial disease. Br J Surg. 2013 Aug;100(9):1172-9. PubMed PMID: 23842831.
  18.  Spronk S, Bosch JL, den Hoed PT, Veen HF, Pattynama PM, Hunink MG. Cost-effectiveness of endovascular revascularization compared to supervised hospital-based exercise training in patients with intermittent claudication: a randomized controlled trial. J Vasc Surg. 2008 Dec;48(6):1472-80. PubMed PMID: 18771879. Epub 2008/09/06. eng..
  19.  Treesak C, Kasemsup V, Treat-Jacobson D, Nyman JA, Hirsch AT. Cost-effectiveness of exercise training to improve claudication symptoms in patients with peripheral arterial disease. Vasc Med. 2004 Nov;9(4):279-85. PubMed PMID: 15678620. Epub 2005/02/01. eng.
  20.  van Asselt AD, Nicolai SP, Joore MA, Prins MH, Teijink JA. Cost-effectiveness of exercise therapy in patients with intermittent claudication: supervised exercise therapy versus a 'go home and walk' advice. Eur J Vasc Endovasc Surg. 2011 Jan;41(1):97-103. PubMed PMID: 21159527. Epub 2010/12/17. eng.
  21.  results not published.
  22.  Shalhoub J, Hamish M, Davies AH. Supervised exercise for intermittent claudication - an under-utilised tool. Annals of the Royal College of Surgeons of England. 2009 Sep;91(6):473-6. PubMed PMID: 19558766. Pubmed Central PMCID: 2966198. Epub 2009/06/30. eng.
  23.  Murphy TP, Cutlip DE, Regensteiner JG, Mohler ER, Cohen DJ, Reynolds MR, et al. Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the claudication: exercise versus endoluminal revascularization (CLEVER) study. Circulation. 2012 Jan 3;125(1):130-9. PubMed PMID: 22090168. Epub 2011/11/18. eng.
  24.  Mazari FA, Khan JA, Carradice D, Samuel N, Abdul Rahman MN, Gulati S, et al. Randomized clinical trial of percutaneous transluminal angioplasty, supervised exercise and combined treatment for intermittent claudication due to femoropopliteal arterial disease. Br J Surg. 2012 Jan;99(1):39-48. PubMed PMID: 22021102.
  25.  Fakhry F, Rouwet EV, den Hoed PT, Hunink MG, Spronk S. Long-term clinical effectiveness of supervised exercise therapy versus endovascular revascularization for intermittent claudication from a randomized clinical trial. Br J Surg. 2013 Aug;100(9):1164-71. PubMed PMID: 23842830.
  26.  Frans FA, Bipat S, Reekers JA, Legemate DA, Koelemay MJ. Systematic review of exercise training or percutaneous transluminal angioplasty for intermittent claudication. Br J Surg. 2012 Jan;99(1):16-28. PubMed PMID: 21928409. Epub 2011/09/20. eng.
  27.  Breek JC, Hamming JF, De Vries J, van Berge Henegouwen DP, van Heck GL. The impact of walking impairment, cardiovascular risk factors, and comorbidity on quality of life in patients with intermittent claudication. J Vasc Surg. 2002 Jul;36(1):94-9. PubMed PMID: 12096264.
  28.  Jongkind V, Akkersdijk GJ, Yeung KK, Wisselink W. A systematic review of endovascular treatment of extensive aortoiliac occlusive disease. J Vasc Surg. 2010 Nov;52(5):1376-83. PubMed PMID: 20598474.
  29.  Lensvelt MM, Reijnen MM, Wallis De Vries BM, Zeebregts CJ. Treatment strategies for extensive chronic SFA occlusions: indications and results. The Journal of cardiovascular surgery. 2012 Feb;53(1 Suppl 1):161-70. PubMed PMID: 22433735..